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3, so it had been unlikely that there was multicollinearity during the a number of linear regression versions. Additionally, we done sensitivity analyses by using urinary creatinine focus (log-transformed) to be a covariate in place of creatinine-adjusted urinary significant metal concentrations and which include interaction phrases in between both harmful large metals (As, Cd, and Pb) or Se; Not one of the urinary creatinine concentration plus the conversation terms was statistically major, and Total associations between urinary heavy metals and blood pressure did not change (Tables S1 and S2).

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The tubes had been washed with fifteen% nitric acid and rinsed with ultrapure drinking water prior to sampling. The collected urine samples were frozen with dry ice, then transported to Japan, and stored at −eighty°C until eventually Evaluation.

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Desk six provides the outcomes of several linear regression analyses analyzing the associations in between urinary large metal concentrations and blood pressure in all contributors (covariates: place, age, intercourse, and BMI). Statistically considerable associations were not uncovered concerning urinary As concentrations and blood pressure level. Urinary concentration of Pb was positively related to both SBP and DBP, though more info urinary Se focus of Se was negatively linked to them. All values of VIF had been less than one.

れます。ミクロのレベルでの変化が起こった後、症状が発生する前に早期発見し、介入することを二次予防と呼

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